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Die Kryokonservierung unbefruchteter Eizellen stellt eine relativ neuartige Technologie zum Erhalt weiblichen Fertilität dar. Immer öfter wird dieses Verfahren dabei auch ohne Vorliegen einer medizinischen Indikation in Anspruch genommen ("Social Egg Freezing"). Der Autor unterzieht - aufbauend auf einer empirischen und rechtlichen Analyse - diese nicht unumstrittene Technik einer ethischen Analyse. Ein spezieller Fokus wird dabei auf die Frage gelegt, in welchem Verhältnis Social Egg Freezing zur philosophischen Frage nach dem guten Leben steht. Hierbei wird das Argument entwickelt, dass ein ernstzunehmendes Gefahrenmoment dieser Technik gerade darin liegt, existentielle Lebensentscheidungen immer weiter aufzuschieben.
Freeze-drying. --- Freeze-drying --- Cultures (Biology) --- Methodology. --- Cryopreservation.
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Almost a decade has passed since the last textbook on the science of cryobiology, Life in the Frozen State, was published. Recently, there have been some serious tectonic shifts in cryobiology which were perhaps not seen on the surface but will have a profound effect on both the future of cryobiology and the development of new cryopreservation methods. We feel that it is time to revise the previous paradigms and dogmas, discuss the conceptually new cryobiological ideas, and introduce the recently emerged practical protocols for cryopreservation. The present books, ""Current Frontiers in Cryobiology"" and ""Current Frontiers in Cryopreservation"" will serve the purpose. This is a global effort by scientists from 27 countries from all continents and we hope it will be interesting to a wide audience.
Cryobiology. --- Freezing --- Low temperature biology --- Biology --- Cold --- Cryopreservation of organs, tissues, etc. --- Low temperatures --- Life Sciences --- Cryobiology --- Plant Biology --- Agricultural and Biological Sciences
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Almost a decade has passed since the last textbook on the science of cryobiology, Life in the Frozen State, was published. Recently, there have been some serious tectonic shifts in cryobiology which were perhaps not seen on the surface but will have a profound effect on both the future of cryobiology and the development of new cryopreservation methods. We feel that it is time to revise the previous paradigms and dogmas, discuss the conceptually new cryobiological ideas, and introduce the recently emerged practical protocols for cryopreservation. The present books, ""Current Frontiers in Cryobiology"" and ""Current Frontiers in Cryopreservation"" will serve the purpose. This is a global effort by scientists from 27 countries from all continents and we hope it will be interesting to a wide audience.
Cryopreservation of organs, tissues, etc. --- Cryoconservation of organs, tissues, etc. --- Cryogenic preservation of organs, tissues, etc. --- Low temperature preservation of organs, tissues, etc. --- Preservation of organs, tissues, etc. --- Cryobiology --- Cryonics --- Life Sciences --- Plant Biology --- Agricultural and Biological Sciences
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Analyzes how the possibility of egg freezing changes what it means to be fertile and to age in the 21st centuryWelcomed as liberation and dismissed as exploitation, egg freezing (oocyte cryopreservation) has rapidly become one of the most widely-discussed and influential new reproductive technologies of this century. In Freezing Fertility, Lucy van de Wiel takes us inside the world of fertility preservation—with its egg freezing parties, contested age limits, proactive anticipations and equity investments—and shows how the popularization of egg freezing has profound consequences for the way in which female fertility and reproductive aging are understood, commercialized and politicized.Beyond an individual reproductive choice for people who may want to have children later in life, Freezing Fertility explores how the rise of egg freezing also reveals broader cultural, political and economic negotiations about reproductive politics, gender inequities, age normativities and the financialization of healthcare. Van de Wiel investigates these issues by analyzing a wide range of sources—varying from sparkly online platforms to heart-breaking court cases and intimate autobiographical accounts—that are emblematic of each stage of the egg freezing procedure. By following the egg’s journey, Freezing Fertility examines how contemporary egg freezing practices both reflect broader social, regulatory and economic power asymmetries and repoliticize fertility and aging in ways that affect the public at large. In doing so, the book explores how the possibility of egg freezing shifts our relation to the beginning and end of life.
Ovum --- Cryopreservation of organs, tissues, etc. --- Human reproductive technology. --- Human reproduction --- Cryopreservation. --- Political aspects. --- Age factors. --- Add-on technologies. --- Affect theory. --- Age-related infertility. --- Anticipation. --- Automation. --- Biocapital. --- Biological clock. --- Biopolitics. --- Biovalue. --- Cloning. --- Cross-border reproductive care. --- Datafication. --- Egg banks. --- Egg donation. --- Egg freezing. --- Embodiment. --- Embryo selection. --- Fertility education. --- Fertility insurance. --- Fertility loans. --- Fertility markets. --- Fertility preservation. --- Fertility. --- Financial inducement. --- Frozen eggs. --- Gender Politics. --- Gender. --- Global biopolitics of ageing. --- History of reproduction. --- Human egg. --- IVF. --- Kinship. --- Life course management. --- Lifestyle. --- Media analysis. --- Medical imagery. --- Mergers and Acquisitions. --- Mitochondrial transfer. --- Older motherhood. --- Oocyte cryopreservation. --- Patenting. --- Political economy of reproduction. --- Posthumous reproduction. --- Precarity. --- Preparedness. --- Queer theory. --- Reproductive ageing. --- Reproductive decision-making. --- Reproductive loss. --- Reproductive politics. --- Reproductive studies. --- SCNT. --- Single women. --- Singlehood. --- Successful ageing. --- Time-lapse embryo imaging.
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Since accidentally discovering the ability of glycerol on protecting cells from freezing damage, many researchers have been pursuing to develop cryopreservation methods of a very wide range of cells and some tissues, and these have found widespread applications in biology and medicine. From the point of view of living organisms, cryopreservation is a useful tool for ex situ conservation of genetic resources together with its contribution on conservation of their biodiversity. Cryopreservation in Eukaryotes includes totally 12 chapters, which have been written by the expert researchers in the field. The chapters are a comprehensive collection of the most frequently used methods for eukaryotes. With this book, every researcher will better understand the principles, background, and current status of cryopreservation in particular organisms.
Cryopreservation of organs, tissues, etc. --- Eukaryotic cells. --- Methodology. --- Eucaryotic cells --- Cells --- Protista --- Cryoconservation of organs, tissues, etc. --- Cryogenic preservation of organs, tissues, etc. --- Low temperature preservation of organs, tissues, etc. --- Preservation of organs, tissues, etc. --- Cryobiology --- Cryonics --- Life Sciences --- Microbiology --- Genetics and Molecular Biology --- Cytology --- Biochemistry
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Azoospermia, defined as the absence of sperm in the ejaculate after examination of the centrifuged specimens, affects about 1% of the male population and 10–15% of infertile men. In about two-thirds of cases, this is caused by severe spermatogenic dysfunction, and it is commonly termed “nonobstructive azoospermia” (NOA) to differentiate it from the less severe form of azoospermia caused by the obstruction of the seminal tract (obstructive azoospermia—OA), the latter affecting the remaining one-third of cases. Managing patients with NOA is challenging due to the severity of spermatogenic dysfunction and the lack of medical treatments, with surgical retrieval of testicular sperm being the only way of enabling some of these patients to father their own biological children. In-depth clinical knowledge is key for supporting clinical reasoning and decision making when counselling patients with NOA, and surgical skill is required to maximize the outcome of surgical procedures that aim to retrieve testicular sperm. The present book is a collection of scientific papers published in a Special Issue of the Journal of Clinical Medicine, authored by some of the most influential researchers in the field. The Special Issue, and thus also this book, were conceived to provide early career reproductive urologists and endocrinologists with an update of the scientific evidence in the field, together with surgical tips.
nonobstructive azoospermia --- micro-TESE --- FSH treatment --- hormonal treatment --- testosterone level --- microdissection testicular sperm extraction --- non-obstructive azoospermia --- management --- infertility --- intracytoplasmic sperm injection --- testicular azoospermia --- sperm selection --- sperm --- cryopreservation --- in vitro maturation --- azoospermia --- diagnosis --- male infertility --- spermatogenic failure --- testis biopsy --- sperm retrieval --- genetic testing --- endocrine evaluation --- review --- hypogonadism --- Sertoli cell-only syndrome --- testicular spermatozoa --- processing --- microfluidics --- new technologies --- genetics --- exome --- WES --- Y chromosome --- cancer --- NOA --- genes --- general health --- ICSI --- offspring health --- microTESE --- prediction model --- n/a
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Regenerative medicine and tissue engineering play significant roles in the treatment of currently intractable conditions, such as chronic heart failure, stroke, chronic osteoarthritis, and other maladies. Regenerative medicine and tissue engineering generally depend on the utilization of stem cells to treat patients but may also utilize mature cells that would not normally be considered as stem cells (e.g., skin). Stem cells (like mature cells) may be obtained from many sources in the body including bone marrow, cord blood, cord tissue, adipose tissue, etc. Although stem cells are often used in therapy immediately upon isolation, in many circumstances, the stem and progenitor cells will be harvested, processed and banked frozen until a later time. Biobanking is a convenient alternative to same-day therapeutic use, in that it allows for patient recovery (e.g., from liposuction), provides time to identify the best treatment options, and may allow for multiple interventions with additional patient inconvenience or risk.
Medicine. --- n/a --- MSCs --- EVs --- exosomes --- tissue regeneration --- immunomodulation --- biobanking --- adult stem cells --- ground-state --- autologous transplantation --- regenerative medicine --- stem cell banking --- newborn stem cells --- perinatal stem cells --- umbilical cord tissue --- umbilical cord blood --- placenta --- Vascular tissue engineering --- human cord blood-derived endothelial cells --- endothelialization --- vascular graft --- Munich Vascular Biobank --- atherosclerosis --- human vascular tissue --- RIN --- RNA fragmentation --- adipose tissue --- cryopreservation --- autologous --- fat grafting --- cryogenic storage --- lipoaspirate --- cosmetic surgery
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Rapid establishment of seedlings in forest regeneration or afforestation sites after planting is a prerequisite for a successful reforestation. Seedling survival after outplanting can be improved by using high-quality seedling material. Seedling quality consists of several features, such as genetic source, morphological properties, nutritional status, stress resistance, and vitality of the seedlings. Field performance of the seedlings is a complex process which can be affected by many nursery and silvicultural practices. Nursery cultural practices strongly affect seedling quality, which is generally at its highest level during the growth period at the nursery. Afterwards, when the seedlings are transported from the nursery to the planting site (including seedling storage, handling, shipping, and planting practices), the quality of seedlings can only remain the same or decline. To ensure successful regeneration, it is important to produce seedlings that retain their high quality until planting, and to establish them quickly in the forest regeneration site.
container parameters --- forest regeneration material --- physiological attributes --- somatic embryogenesis --- Quercus rubra --- antioxidant enzymes --- nursery production --- shortleaf pine --- historical perspective --- maturation --- Appalachia --- bulk density --- Quercus robur L. --- rabbit --- western larch --- Picea abies L. Karst. --- sessile oak --- climate change --- physiological quality --- nursery culture --- Fennoscandia --- pedunculate oak --- elk --- seeds --- survival --- small mammal --- loblolly pine --- Norway spruce --- white oak --- growing media --- germination --- morphological attributes --- embling production --- mechanization --- browse --- contractor --- field performance --- reforestation --- white-tailed deer --- forest biotechnology --- cultural practice --- hybridization --- nutrients --- silviculture --- black locust --- scarification index --- seedling quality --- tree planting machine --- seed size --- herbicide --- artificial regeneration --- restoration ecology --- porosity --- northern red oak --- cryopreservation --- leaf senescence --- tree seedling --- Douglas fir --- Quercus --- growth --- mine reclamation --- forestry
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Rabbit livestock is especially important in the Mediterranean area and in the semi-arid zones of Africa, Asia, and America, representing a valuable alternative source of good animal protein of high quality (low fat and low cholesterol). However, rabbit husbandry should adapt to be a competitive and sustainable sector. In addition, it must maintain a balance between rabbit welfare, customer demands, and breeder requirements. Then, improvement in breeding systems is needed and may involve avoiding hormones and antibiotics in rabbit management; enhancing the efficiency of reproductive procedures such as artificial insemination systems and freezing of semen and embryos; extending the productive lifespan of does; improving genetic selection systems; and adjusting nutritional systems to optimize the physiological status of animals and the immune response. This Special Issue concerns all these challenges in increasing rabbit productivity and sustainability.
Oryctolagus cuniculus --- SNPs --- SLAF-seq --- genome-wide association study --- growth trait --- myeloperoxidase --- lysozyme --- rabbits --- viral infection --- rabbit hemorrhagic disease --- goji berries --- rabbit --- insulin resistance --- leptin --- non-esterified fatty acids --- pregnancy --- lactation --- body condition score --- principal component analysis --- gene expression --- endometrium --- oviduct --- spermatozoa --- seminal plasma --- inflammation --- angiogenesis --- corpus luteum --- reproduction --- genomic selection --- imputation --- litter size --- genomic simulation --- artificial insemination --- antibiotics --- antibacterial activity --- semen quality --- reproductive performance --- sperm quality --- cryopreservation --- animal model --- assisted reproductive technology --- CTSS --- granulosa cells --- proliferation --- apoptosis --- hormone secretion --- body composition --- fertility --- kits born alive --- rabbit does --- feed intake --- free tri-iodothyronine --- thyroxine --- insulin --- glucose --- corticosterone --- NEFA --- fetus --- placenta
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Nowadays, assisted reproductive technologies (ARTs) have a pivotal role not only in achieving fertilization in subfertile animals, but they are also involved in the management of the herd, decreasing disease spread and even allowing offspring sex selection. Nonetheless, there are differences between species or even within species that have led researchers worldwide to focus on those differences in order to bypass these specific difficulties. This Special Issue, titled “The Era of Assisted Reproductive Technologies Tailored to the Specific Necessities of Species, Industry and Case Reports” and published in Animals, is composed of 12 original manuscripts and three reviews that offer an overview of current and future ARTs used to improve reproductive outcomes, mainly focused on farm animals, such as horse, pig, bovine, rabbit and ovine species. Thus, the Special Issue covers information from the classical point of view, including comparative studies of different semen extenders, to the most advanced technologies of sperm selection by thermotaxis or chemoattractants, as well as the improvement of sperm features by red light irradiation. The female and embryo contributions to ART outcomes are also covered, for instance, with a study that improves our knowledge by the metabolomic description of follicular fluid composition or the description of better culture conditions of oocytes. In brief, this Special Issue provides a balanced overview of emerging techniques and technologies used to preserve, improve, rescue or even create fertility for domestic farm animals with high economic impact.
IVM --- oocytes --- equine --- metabolomic --- embryo transfer --- reproductive fluids --- pregnancy --- vitrification --- calving --- selection programme --- embryo vitrification --- Gompertz growth curve --- biobanking --- reproductive performance --- stallion sperm --- capacitation --- penicillamine --- thermotaxis --- selection --- BMP15 --- ram --- semen --- semen freezing --- semen extender --- stallions --- semen quality --- fertilizing ability --- Tris --- boar spermatozoa --- perfluorinated compounds --- PFHxS --- PFOS --- spermatozoa toxicology --- glucocorticoid receptor --- gene expression --- RT-qPCR --- seminal plasma --- female genital tract --- rabbit --- spermatozoa --- oocyte --- in vitro fertilization --- extracellular vesicles --- assisted reproductive technologies --- embryo --- oocyte competence --- livestock production --- assisted reproductive technology --- embryo development --- micromanipulation --- in vitro production --- nanoparticles --- liposomes --- exosomes --- cryopreservation --- sheep --- ovary storage --- transport --- in vitro embryo production --- sperm selection --- chemotaxis --- IVF --- IVC --- porcine --- cryopreserved sperm --- sperm–oviduct interaction --- ARTs --- equines --- horse --- sperm --- red light irradiation --- extender --- straw
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